Caltech scientists build DNA logic circuits that run in a test tube

We've seen DNA logic before, but a new variety at Caltech has created a set of circuits that can work in salt water, possibly paving the way for cell-based computers. The researchers created a small series of circuits and included gates to perform all the binary logic functions: AND, OR, and NOT. Each gate, a set of DNA strands, receives DNA molecules as input and spits out different ones as output.
They've succeeded in building 12 gates in a cascade five layers deep - pretty simple compared to your average microchip, but nonetheless pretty impressive!